Titin compliance refers to the ability of the giant protein titin to stretch or unfold under force. Titin is the largest protein in the human body and acts as a molecular spring in muscle fibers, playing a crucial role in muscle elasticity and function. Research in this area aims to understand how titin compliance affects muscle performance, flexibility, and overall muscle health. Studies in titin compliance may have implications for the development of treatments for muscle-related disorders and the design of biomaterials for engineering muscle tissues.